CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology is a simple but powerful tool for genome editing. This tool enables life science researchers to easily edit DNA sequences and modify gene function. It has many potential applications include correcting genetic defects, treating and preventing the spread of diseases and improving crops. By delivering the CRISPR enzyme Cas9 nuclease coupled with synthetic guide RNA (gRNA) into a cell, the cell’s genome can be cut at a desired location, that allows existing genes to be removed or add new ones.
How does it work?
Of course, all this is only useful if you’re a bacterium. So how do we turn an anti-virus defence mechanism into something that could let us edit human genomes at will?
Rather than relying on bacteria to create the molecules for them, scientists have worked out how to create their own versions of the CRISPR molecules in the lab. To start with, they need to work out the section of DNA that they want to target. For a condition sickle-cell anaemia, which is caused by a fault in a single gene, this is relatively easy, since we’ve already sequenced the gene that causes this disease and so know exactly the genetic code that we’re trying to target.
Top Players: the key players operating in the CRISPR Technology market include Thermo Fisher Scientific Inc., Merck KGaA, Horizon Discovery Group plc, Cellecta, Inc, GeneCopoeia, Inc., New England Biolabs, OriGene Technologies, Inc., GenScript, Integrated DNA Technologies, Inc. and Agilent Technologies, Inc.
Technology Growth Regions:
North America held over major share in the CRISPR Technology market in 2017 owing to significant research carried out in order to develop novel therapeutics for disease targeting and high adoption of genome editing technique for germline modifications. North America is expected to collectively contribute towards the growth of CRISPR Technology market owing to the presence of major market players and also the development of technologically advanced products of CRISPR technology is expected to influence the CRISPR technology market growth.
The Asia-Pacific region is expected to exhibit highest CAGR during the forecast period due to many applications in developing economies of the region for animal disease and human disease treatment. Also, the rapid economic growth in this region coupled with diversified population and large patient pool, drives CRISPR Technology market in this region.