Adrenoleukodystrophy Market Size and Share

Adrenoleukodystrophy (ALD) is an X-linked recessive genetic disorder caused by the abnormality in the ABCD1 gene present on the X chromosome that leads to the accumulation of very-long-chain fatty acids (VLCFAs) in the brain, nervous system, and adrenal gland.

Cerebral Adrenoleukodystrophy (CALD) is the most severe form of ALD, characterized by a breakdown of the protective sheath known as myelin, which surrounds and protects the nerve cells responsible for thinking and muscle control. The symptoms of CALD usually occur in early childhood and progress rapidly if untreated, leading to severe loss of brain function and eventually death in most patients.

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