Research on Cell Line Development: A Systematic Review

Cytology is study of function and structure of cells whereas histology is the branch of science which deals with study of microscopic tissue structure. Both cytology and histological studies are applied to I diagnosis of infectious diseases, inflammatory diseases and autoimmune disease. Histology and Cytology studies also help in drug designing, enzyme study, cancer detection and many others.

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The cell line is established cell culture, which gets increased numerous times when supplied with the growth medium and space for growth. Different cell lines can be made from different cells. The cell line plays a vital role in the study of cytology. The cell line enables stepwise alterations in the structure, physiology, and genetic makeup of cells under a customized environment.

The cell line development market majorly consists of the players such as Merck KGaA, Thermo Fisher Scientific Inc., Selexis SA (JSR Corporation), BioFactura, Inc., Corning Incorporated, Sartorius AG, Lonza, GENERAL ELECTRIC, LakePharma, Inc., and WuXi AppTec Group amongst others.

The cell line development is a crucial and invariable part of this field as it helps understand how to treat a wide range of medical conditions, from broken bones to neurodegenerative diseases. Further, the regenerative medicines use cell-based models that have the potential to help the researchers in early-intervention treatment for degenerative diseases and traumatic injuries. Thus, the rise in adoption of regenerative medicines is fostering the demand for cell line development in the coming years.