June 19, 2020

What is Multiple Sclerosis - Brain Health

Multiple Sclerosis is a disease related to brain and spinal cord in which the immune system attacks the protective sheath i.e. myelin that covers the nerve fibers and results in communication problems between the brain and the rest of the body.

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MS is not considered a hereditary disease; however, a number of genetic variations have been shown to increase the risk. Some of these genes appear to have higher levels of expression in microglial cells than expected by chance.

The probability of developing the disease is higher in relatives of an affected person, with a greater risk among those more closely related.[8] In identical twins both are affected about 30% of the time, while around 5% for non-identical twins and 2.5% of siblings are affected with a lower percentage of half-siblings. If both parents are affected the risk in their children is 10 times that of the general population. MS is also more common in some ethnic groups than others.

Many microbes have been proposed as triggers of MS, but none have been confirmed. Moving at an early age from one location in the world to another alters a person's subsequent risk of MS. An explanation for this could be that some kind of infection, produced by a widespread microbe rather than a rare one, is related to the disease.

Proposed mechanisms include the hygiene hypothesis and the prevalence hypothesis. The hygiene hypothesis proposes that exposure to certain infectious agents early in life is protective, the disease is a response to a late encounter with such agents.

The prevalence hypothesis proposes that the disease is due to an infectious agent more common in regions where MS is common and where, in most individuals, it causes an ongoing infection without symptoms. Only in a few cases and after many years does it cause demyelination. The hygiene hypothesis has received more support than the prevalence hypothesis.

MARKET DYNAMICS

The Multiple Sclerosis market is anticipated to grow in the forecast period owing to driving factors such as rising number of multiple sclerosis incidences, increasing initiatives from the government for favorable reimbursements, and rise in number of R&D activities of pharmaceutical companies. Nevertheless, high cost associated with therapeutics and side effects of the drugs may hamper the market growth during the forecast period.

MARKET SCOPE

The "Global Multiple Sclerosis Market Analysis to 2027" is a specialized and in-depth study of the pharmaceutical industry with a special focus on the global market trend analysis. The report aims to provide an overview of Multiple Sclerosis market with detailed market segmentation by type and geography. The global Multiple Sclerosis market is expected to witness high growth during the forecast period. The report provides key statistics on the market status of the leading Multiple Sclerosis market players and offers key trends and opportunities in the market.