August 25, 2020

Nanoinformatics and DNA-Based Computing: Catalyzing Nanomedicine

Five decades of research and practical application of computers in biomedicine has given rise to the discipline of medical informatics, which has made many advances in genomic and translational medicine possible.

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Developments in nanotechnology are opening up the prospects for nanomedicine and regenerative medicine where informatics and DNA computing can become the catalysts enabling health care applications at sub-molecular or atomic scales.

Nanoinformatics: an emerging area of information technology at the intersection of Bioinformatics, Computational Chemistry and Nanobiotechnology.
source: pixabay.com

Nanoinformatics can accelerate the introduction of nano-related research and applications into clinical practice, leading to an area that could be called “translational nanoinformatics.” At the same time, DNA and RNA computing presents an entirely novel paradigm for computation.

Nanoinformatics and DNA-based computing are together likely to completely change the way we model and process information in biomedicine and impact the emerging field of nanomedicine most strongly.

A new generation of nanodevices for diagnosing and treating children with genetic diseases and cancer includes the use of nanoparticles for diagnostic imaging during pregnancy, nano-based newborn screening tests for genetic abnormalities and mutation detection for cystic fibrosis using a nanoparticle based bio-sensing system. Similarly, nanomechanical approaches study the effect of drugs on Pseudomonas aeruginosa, the causative agent of chronic lung infections in patients affected by cystic fibrosis.

Nanoinformatics can contribute critically to some of the above. Examples include: describing the use of computer simulations for improving targeted delivery of magnetic aerosol droplets to specific lung regions to treat asthma, cystic fibrosis, respiratory infection, or lung cancer. Stone et al. analyzed the potential toxicity of air pollution nanoparticles in children and adults in terms of cellular and molecular interactions involved in inducing oxidative stress and inflammation.

DYNAMICS

The nanomedicines market is anticipated to grow in the forecast period owing to driving factors such as, large amount of R&D happen in this field and the rising number of cases of cancer. The new applications of nanodevices are expected to offer significant growth opportunities in the global nanomedicines market during the forecast period.

SCOPE

The "Global Nanomedicines Market Analysis to 2027" is a specialized and in-depth study of the pharmaceuticals industry with a special focus on the global market trend analysis. The report aims to provide an overview of nanomedicines market with detailed market segmentation by product, application, type, and geography. The global nanomedicines market is expected to witness high growth during the forecast period. The report provides key statistics on the market status of the leading nanomedicines market players and offers key trends and opportunities in the market.

Source: The Insight Partners & nature.com