May 11, 2020

Stem Cell Treatment for COVID-19; Doctors Divided on Its Scope

As the world waits for a vaccine for COVID-19, multiple treatment options are being considered to mitigate the severity of impact for patients affected by the disease. Stem cell therapy has emerged as a candidate, with isolated victories across the world pointing towards its potential.

A stem cell has the unique ability to develop into specialised cell types in the body. These may be used to replace cells and tissues that have been damaged or lost due to a disease or infection.

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The treatment involves procuring stem cells from a host of possible sources (the patient’s own body or from a donor) and introducing them in the diseased person for the regeneration and repair of damaged tissues. It has been found to be helpful in certain degenerative, autoimmune and skin disorders, and its application for many other conditions is being explored.

But how does it factor into COVID-19 research, what is the evidence for its efficacy and how are doctors approaching the development?

Stem cells are preliminary body cells from which all other cells with specialized functions are generated. Under controlled environment in the body or a clinical laboratory, these cells divide to form more cells called daughter cells. Due to the advent of modern health science, these cells play a major role in understanding the occurrence of diseases, generation of advanced regenerative medicines, and drug discovery. There are certain sources such as embryo, bone marrow, body fats, and umbilical cord blood amongst others, where stem cells are generated. The global stem cell therapy industry is driven by factors such as increasing awareness related to the stem cells therapy in effective disease management and growing demand for regenerative medicines.

Researchers are further investigating stem cell therapy in autoimmune disorder. Other adult stem cells based treatments are under clinical trials. Hematopoietic stem cells are currently used for treating more than 80 medical diseases, which include diseases of the immune system, blood disorders, neurological disorders, metabolic disorders, genetic disorders, and several types of cancers like leukemia, lymphoma, etc.

Leading companies operating in the stem cell therapy

Medipost, pharmicell Co., Ltd., HolostemTerapieAvanzate S.R.L., Mesoblast Ltd., U.S. Stem Cell, Inc., Biotime, Inc., RichSource, Caladrius, TiGenix NV (Takeda Pharmaceuticals), and GeneaBiocells among others.

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Reference

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