Perspectives and New focuses of Rat Model
There is a need for preclinical animal models such as mice and rats that are used to predict drug effectiveness and toxicity in humans. Due to their genetic similarities to humans as well as their large supply and ease of manipulation, rats are widely used. For instance, by inactivating or silencing an existing gene and replacing it with an artificial piece of DNA, Knockout rats are formed, resulting in the loss of gene activity.
This leads to improvements in the phenotypic features of the rat, such as appearance, behavior, and other biochemical characteristics that are similar to human being. The high growth in using rat models can be due to their use to carry out researches on disease such as oncology, obesity, heart disease, diabetes, arthritis, drug abuse, anxiety, and other.
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Top Key Players:
- Charles River Laboratories International,
- Envigo
- Taconic Biosciences
- Horizon Discovery Group
- genOway
- Laboratory Corporation of America Holdings
- Transposagen Biopharmaceuticals
- Transviragen
- Janvier Labs
- Biomere
Rat model market is driving due to factors such as advancements in gene editing tools set to augment the demand for rat models, advantages offered by rats over mice, continuous support in the form of investments and grants, increased demand for personalized humanized rat models due to growing consumption of personalized medicines. However, factors such as, regulations & laws formulated for ethical use of animals and availability of alternatives to animal models through advance technologies is expected to hamper the market growth.
Rat Model Industry: Segment Analysis
By Model Type ( Outbred Rats, Inbred Rats, Knockout or Genetically Modified Rats, Hybrid or Congenic Rats, Conditioned or Surgically Modified Rats, Immunodeficient Rats ); Service ( Breeding, Cryopreservation, Quarantine, Rederivation, Model in licensing, Genetic Testing, Other Services ); Therapeutic Area ( Toxicology, Oncology, Immunology and Inflammation, Neurology, Diabetes, Other Therapeutic Areas ); Technology ( CRISPR, Microinjection, Embryonic Stem Cell Injection, Nuclear Transfer, Other Technologies ); End User ( Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, Contract Research Organizations (CROs))
The report analyzes factors affecting transcriptomics technologies market from both demand and supply side and further evaluates market dynamics effecting the market during the forecast period i.e., drivers, restraints, opportunities, and future trend. The report also provides exhaustive PEST analysis for all five regions namely; North America, Europe, APAC, MEA and South & Central America after evaluating political, economic, social and technological factors effecting the transcriptomics technologies market in these regions.