What is sildenafil and how does it restore erectile function?
When Viagra became available in 1998, it completely transformed the treatment procedure for erectile dysfunction, or ED. Before this medication was introduced to the market, therapies for EDmainly involved physical procedures.
They consisted of non-tablet treatments like penile injections and suppositories. These treatments can cause unwanted side effects like a burning sensation. In addition, they tend to stay effective for less time than medication which is often viewed as an inconvenience.
What is sildenafil mechanism of action?
Sildenafil, on the other hand, stays effective for up to six hours allowing plenty of time for sexual circumstances. Being a PDE5 inhibitor, sildenafil 100mg tablets reduce the activity of an enzyme called phosphodiesterase type 5 (PDE5).
Sometimes, this enzyme is responsible for causing blood vessels to become tight and constricted. By limiting the function of PDE5, sildenafil relaxes blood vessels. This allows more blood to move freely into the penis during sexual stimulation.
The fortuitous discovery of sildenafil
Interestingly, this PDE5 inhibitor was not originally intended to treat erection problems. Before Viagra was approved by the FDA, several studies were conducted.They were carried out to assess the safety and efficacy of this medication for the purpose of treating cardiovascular problems like pulmonary arterial hypertension.
What is sildenafil used for today all changed when a study took place in the early nineties.It involved 38 patients who received sildenafil so researchers could evaluate this medication for the treatment of cardiovascular conditions. The researchers instructed the men to take varying doses of sildenafil 3 times a day.
An interesting side effect that was reported among 3 of the 9 men who took 50mg was an increased tendency to experience erections. The same side effect was reported by 5 of the 8 men who took 75mg doses. Soon after this study, the primary use of this medication was converted from heart health to an effective oral treatment for ED.
What is sildenafil like when used?
Contrary to what some people may think, this medication does not directly cause an erection. You and your partner will need to participate in foreplay to notice the effect. Follow these usage guidelines for best results:
· The active ingredient needs time to become entirely effective so take one tablet at least 30 minutes before sexual activity.
· The safe daily dose is 100mg so avoid taking more than one tablet per day.
· The effective time frame is about four to six hours which allows sufficient time for sexual circumstances.
Order online for 24-7 support
The patent for Viagra expired in 2013 and the more affordable generic version can now be purchased online. In terms of composition and quality,generic sildenafil is identical to Viagra. We supply sildenafil at cost-effective prices. What is sildenafil and how should it be used for best results?
You may be able to answer this now so place an order today and successfully treat ED. And if you have any questions customer support is available round the clock for your convenience.
Resource Link: http://articlescad.com/article/show/126849