iPad only — no
Could not maintain my usual lifestyle with an iPad Air 2020 + Apple Pencil 2 + Logitech Combo Touch keyboard case and with no computer at all.
iPad screen seems to be scratchable for me from my older iPad experiences. Also, this Air 4 I have is not rigid at all (unlike older models I had) and even while writing with thew Pencil, the screen gets colorful waves at times. This does not do anything bad to it, just does not feel very reliable.
When I was trying to upload something to YouTube or somewhere else, the apps could close in the background -> progress lost -> impossible to do normal actions.
When I was writing a post in teletype web, while I was scrolling, a whole paragraph of text disappeared (once, but damn was I upset at that particular moment, trying to convince myself that it was not worth being published; had to retype the whole passage later anyway: equipment should work, period).
Also, it's impossible to have a video chat with someone and write notes at the same time: I would not be really visible from a normal angle "en face" in that scenario.
Only a couple of examples from my life. Does not work for me. Don't get tempted to give away your computer too fast while being "inspired" after a series of YT videos. Unless you think twice at least :D