November 26, 2020

Glycobiology Market – Insights

The term glycobiology is a branch of biology that deals with study of structure, function, and biosynthesis of saccharides (carbohydrates and carbohydrates containing molecules). Glycoconjugates is the general classification for carbohydrates covalently linked with other chemical species such as proteins, peptides, lipids and saccharides. Glycoconjugates and polysaccharides play a vital structural role in connective tissues.

The global glycobiology market is estimated to account for US$ 1,007.4 Mn in terms of value in 2020 and is expected to reach US$ 2,397.5 Mn by the end of 2027.

Global Glycobiology Market: Drivers

Glycans impact tumor proliferation, hematogenous metastasis, invasion and angiogenesis. Therefore, increasing prevalence of cancer is expected to propel growth of the global glycobiology market over the forecast period. For instance, according to the World Health Organization, around 18.1 million new cases and 9.6 million deaths were registered due to cancer worldwide in 2018.

Moreover, high incidence of HIV/AIDS is also expected to aid in growth of the market. For instance, according to Joint United Nations Program on HIV/AIDS, 37.9 million people globally were living with HIV at the end of 2018.

North America region held dominant position in the global glycobiology market in 2018, accounting for 44.3% share in terms of value, followed by Europe.

Global Glycobiology Market: Restraints

Complex structure of glycans is expected to hinder growth of the global glycobiology market.  Unlike DNA or proteins, glycans do not have linear structure. Conventional sequence comparison methods cannot be applied directly to glycan comparison as structure and mechanism of glycans are completely different from DNA or proteins, which makes it more complex for analyzing. DNA or proteins have template sequences to synthesize primary structure, which are uniquely identified by template sequences. However, glycans do not have a template structure. Structure of glycan is determined by substrate specificity of glycosyl-transferases.

Moreover, high costs of spectrometry and high performance liquid chromatography are also expected to limit growth of the market.

Global Glycobiology Market: Opportunities 

R&D in glycans at glycobiology expected to offer lucrative growth opportunities for players in the glob For instance, in February 2020, researchers from University of Minho, Portugal, reported development of a neurocompatible strategy to image temporal distribution of glycoproteins during neuronal development using Cu-free click chemistry.

Moreover, increasing focus on manufacturing anti-cancer drugs is also expected to aid in growth of the market. For instance, in January 2020, researchers from Universidade do Porto, Portugal, reported assessment of the role of O-glycosylation using glycoengineered gastric cancer models in the detection of CD44v9 – a major protein splice variant isoforms expressed in human gastrointestinal cancer cells—by monoclonal antibodies.

Enzymes segment in the global glycobiology market was valued at US$ 487.1 Mn in 2019 and is expected to reach US$ 1,371.0 Mn by 2027 at a CAGR of 13.6% during the forecast period.

Market Trends/Key Takeaways

Increasing adoption of viscosupplementation and facial aesthetic using hyaluronic acid is aiding growth of the market. Hyaluronan, a natural occurring glycosaminogen, is used in viscosupplementation and tissue fillers for volume restoration in facial rejuvenation.

Replacement of conventional glycoanalysis approaches with advanced techniques is also boosting growth of the market. Conventional methods for analysis of glycoforms in complex glycoproteins such as gel electrophoresis and elemental analysis are rapidly getting replaced by new approaches such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS).

Global Glycobiology Market: Competitive Landscape

Major players operating in the global glycobiology market include, Merck KGaA, Bio-Techne Corporation, Bruker Corporation, Thermo Fisher Scientific, Inc., Shimadzu Corporation, Plexera Bioscience LLC, New England Biolabs Inc., Agilent Technologies, Inc., and ProZyme, Inc.

Global Glycobiology Market: Key Developments

Major players in the market are focused on adopting various marketing strategies to expand their customer base. For instance, in February 2020, New England Biolabs demonstrated its next generation sequencing portfolio at 2020 Advances in Genome Biology and Technology (AGBT) General Meeting, held in the U.S.

Players in the market are also focused on adopting partnership strategies to expand their product portfolio. For instance, in November 2019, MOBILion Systems, Inc. partnered with researchers at the University of Georgia, for R&D in glycans and glycoproteins.

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