The development of a strong aquaculture industry is dependent, in part, on advances in the diagnosis and treatment of fish diseases such as vibriosis. Vaccination is one method of lowering the risks associated with the occurrence of disease. The vaccination of large populations of marine animals, however, presents special problems and considerations. The delivery methods employed, for example, must be effective not only from the point of view of protection against infection but they must also be cost-effective. This review attempts to assess some of the currently employed vaccine delivery methods, as well as describing emerging technologies which may have application in the aquaculture industry.