To help focus the global search for a treatment, the researchers aim to provide a comprehensive resource of possible lines of attack against SARS-Cov-2 and related coronaviruses.

Some groups may face a disproportionate mental health impact during the COVID-19 pandemic. These include people of color, migrants, and people of various ethnic backgrounds. In this Special Feature, we dive deeper into the issue.

To help focus the global search for a treatment, the researchers aim to provide a comprehensive resource of possible lines of attack against SARS-Cov-2 and related coronaviruses.

Next-Generation Sequencing technology provides remarkable opportunities to characterize personal or individual genome sequencing and to identifying mutations relevant for disease diagnosis and therapy. The Whole-Exome sequencing using Next-Generation Sequencing (NGS) is promoting popularity in the human genetics community due to the reasonable costs, feasible data quantity and forthright interpretation of analysis results. This review discusses methods and the challenges in the analysis of NGS data and their potential applications in clinical diagnosis in the Next-Generation Exome sequencing.

While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods.